Otitis media with effusion (glue ear) is the most frequent cause of deafness in children we investigated the role of gastric juice reflux in this disease we measured pepsin concentrations in middle ear effusions from children using elisa and enzyme activity assays 45 (83%) of 54 effusions contained pepsin/pepsinogen at concentrations of up to 1000-fold greater than those in serum. Acid reflux and glue ear. Glue ear and acid reflux 10 foods (
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